Research Assistant
We are looking for a highly motivated Research Assistant to join our collaborative team in our efforts towards redefining the early detection and treatment of lethal prostate cancer through translational research efforts.
Our laboratory team have developed a ground-breaking blood test which is continues to be rapidly developed, with the promise of transforming early cancer detection through the evaluation of circulating tumour DNA. We are also developing early disease models from patient-derived tissues, establishing accurate and reliable primary organoid cultures to aid in our study of the behaviour of early stage high-risk prostate cancer. The application of CRISPR-Cas9 gene editing to primary cell cultures provides an exciting window into the genetic dependencies of cancer cells taken from patients within the Cambridge diagnostic cancer pathway. Our therapeutics work, leverages insights from these model systems, as well as the assessment of specimens from clinical trials (NCT02324998). We are exploring the mechanism of action of DNA damaging agents in prostate cancer using cellular and biochemical assays, and with a view to developing novel biomarkers of response that can be rapidly integrated into clinical practise.
The Research Assistant will work closely with postdocs, students and collaborators from molecular diagnostics labs, clinicians, and industry. You will contribute to the development and testing of assays and model systems. Experience with mammalian cell/organoid culture, patient tissue handling, method optimisation, high-throughput genomic assays or molecular diagnostics methods would be an advantage. You will be able to work under your own initiative, and contribute to various projects within the lab, as well as pursuing your own. You will develop experience in a range of cutting-edge techniques and provide support to the day to day running of the laboratory.
Your work will be supported by academic and clinical mentors, working alongside computational and experimental researchers. Effective coordination with colleagues and collaborators will be key in this role, as will enthusiasm and innovative thinking to maximise impact in these multidisciplinary projects. This post will be ideal for a highly motivated individual with experience as a Research Assistant, or someone looking to increase their experience prior to starting a PhD.
Apply online
Closing date
2 November 2022
Our laboratory team have developed a ground-breaking blood test which is continues to be rapidly developed, with the promise of transforming early cancer detection through the evaluation of circulating tumour DNA. We are also developing early disease models from patient-derived tissues, establishing accurate and reliable primary organoid cultures to aid in our study of the behaviour of early stage high-risk prostate cancer. The application of CRISPR-Cas9 gene editing to primary cell cultures provides an exciting window into the genetic dependencies of cancer cells taken from patients within the Cambridge diagnostic cancer pathway. Our therapeutics work, leverages insights from these model systems, as well as the assessment of specimens from clinical trials (NCT02324998). We are exploring the mechanism of action of DNA damaging agents in prostate cancer using cellular and biochemical assays, and with a view to developing novel biomarkers of response that can be rapidly integrated into clinical practise.
The Research Assistant will work closely with postdocs, students and collaborators from molecular diagnostics labs, clinicians, and industry. You will contribute to the development and testing of assays and model systems. Experience with mammalian cell/organoid culture, patient tissue handling, method optimisation, high-throughput genomic assays or molecular diagnostics methods would be an advantage. You will be able to work under your own initiative, and contribute to various projects within the lab, as well as pursuing your own. You will develop experience in a range of cutting-edge techniques and provide support to the day to day running of the laboratory.
Your work will be supported by academic and clinical mentors, working alongside computational and experimental researchers. Effective coordination with colleagues and collaborators will be key in this role, as will enthusiasm and innovative thinking to maximise impact in these multidisciplinary projects. This post will be ideal for a highly motivated individual with experience as a Research Assistant, or someone looking to increase their experience prior to starting a PhD.
Apply online
Closing date
2 November 2022
